Pharma Research
Our comprehensive portfolio includes psychometrically validated clinical outcome assessments (COAs) that measure change in a variety of areas and symptoms. See how our assessments are being utilized in today’s clinical research.
Growth Scale Values (GSVs)
Published Research:
Review the published research spanning numerous diverse clinical areas.
Bayley® Scales of Infant and Toddler Development
Association between head circumference at two years and second and fifth year cognition
Beena Koshy, Manikandan Srinivasan, Timiri Palani Murugan, Anuradha Bose, Pamela Christudoss, Venkata Raghava Mohan, Sushil John, Reeba Roshan & Gagandeep Kang
Early Life Beef Consumption Patterns Are Related to Cognitive Outcomes at 1–5 Years of Age: An Exploratory Study
Victoria C. Wilk, Michelle K. McGuire, and Annie J. Roe
Effects of prenatal exposure to pyrethroid pesticides on neurodevelopment of 1-year- old children: A birth cohort study in China
Zhiye Qi, Xiaoxiao Song, Xia Xiao, Kek Khee Loo, May C. Wang, Qinghua Xu, Jie Wu, Shuqi Chen, Ying Chen, Lingling Xu, Yan Li
Effects of single and combined exposure to lead and stress during pregnancy on offspring neurodevelopment
Xiangrong Guo, Shiwei Jiang, Jian Xu, Ying Tian, Fengxiu Ouyang, Xiaodan Yu, Junxia Liu, Chonghuai Yan, Jun Zhang
Growth and neurodevelopment in low birth weight versus normal birth weight infants from birth to 24 months, born in an obstetric emergency hospital in Haiti, a prospective cohort study
Marjorie Hilaire, Xanthi D. Andrianou, Annick Lenglet, Cono Ariti, Kessiane Charles, Sonja Buitenhuis, Daan Van Brusselen, Harriet Roggeveen, Elizabeth Ledger, Rodnie Selva Denat & Lindsay Bryson
Head growth during neonatal intensive care unit stay is related to the neurodevelopmental outcomes of preterm small for gestational age infants
Hannah Cho, Ee-Kyung Kim, In Gyu Song, Ju Sun Heo, Seung Han Shin, Han-Suk Kim
Head Growth and Neurodevelopment of Preterm Infants with Surgical Necrotizing Enterocolitis and Spontaneous Intestinal Perforation
Shin, Seung-Han, Ee-Kyung Kim, Seh-Hyun Kim, Hyun-Young Kim, and Han-Suk Kim
Infantile neurodevelopmental outcome after fetoscopic laser photocoagulation for twin-to-twin transfusion syndrome: the first prospective experience from Iran
Nazila Mesbah, Vajiheh Marsousi, Laleh Eslamian, Hadi Montazerlotfelahi, Alireza A. Shamshirsaz, Kamran Hessami, Ashraf Jamal, Maryam Noorzadeh, Mahsa Naemi & Marjan Ghaemi
New Approach to Intelligence Screening for Children With Global Development Delay Using Eye-Tracking Technology: A Pilot Study
Hong Xu, Xiaoyan Xuan, Li Zhang, Wenxin Zhang, Min Zhu and Xiaoke Zhao
Pre-eclampsia Complicated With Maternal Renal Dysfunction Is Associated With Poor Neurological Development at 3 Years Old in Children Born Before 34 Weeks of Gestation
Noriko Yoneda, Satoshi Yoneda, Sayaka Tsuda, Mika Ito, Arihiro Shiozaki, Hideki Niimi, Taketoshi Yoshida, Akitoshi Nakashima and Shigeru Saito
The ability of Bayley-III scores to predict later intelligence in children born extremely preterm
Johanna Månsson, Karin Källén, Eva Eklöf, Fredrik Serenius, Ulrika Ådén, Karin Stjernqvist
Psychometric properties of the Beck Depression Inventory-II in progressive supranuclear palsy
Sofia Cuoco, Arianna Cappiello, Filomena Abate, Maria Francesca Tepedino, Roberto Erro, Giampiero Volpe, Maria Teresa Pellecchia, Paolo Barone, Marina Picillo
Neuroimaging Correlates of Patient-Reported Outcomes in Multiple Sclerosis
Dejan Jakimovski, Taylor R Wicks, Niels Bergsland, Michael G Dwyer, Bianca Weinstock-Guttman, Robert Zivadinov
Effects of Mindfulness-Based Interventions (MBIs) in Patients with Early-Stage Alzheimer’s Disease: A Pilot Study
M. V. Giulietti, R. Spatuzzi, P. Fabbietti, and A. Vespa
Impact of depression on the perception of fatigue and information processing speed in a cohort of multiple sclerosis patients
Madia M. Biasi, Alessia Manni, Ilaria Pepe, Chiara Abbatantuono, Daphne Gasparre, Pietro Iaffaldano, Marta Simone, Maria F. De Caro, Maria Trojano, Paolo Taurisano & Damiano Paolicelli
Swimming Activity Alleviates the Symptoms of Attention: Deficit Hyperactivity Disorder (ADHD) a Case Report
Smaragda Skalidou, Andreas Anestis, Nicoletta Bakolas, Georgia Tsoulfa and Konstantinos Papadimitriou
Validity of the short-form five-item Problem Area in Diabetes questionnaire as a depression screening tool in type 2 diabetes mellitus patients
Donovan Tay, Marvin Chua, Joan Khoo
The relationship between physical function and psychological symptoms in Parkinson's disease: A systematic review and meta-regression analysis
Philip Hodgson, Alastair Jordan, Charikleia Sinani, Divine Charura, Samuel T. Orange
Predictive Model of Anxiety and Depression Perception in Multiple Sclerosis Patients: Possible Implications for Clinical Treatment
María Cuerda-Ballester, Antonio Bustos, David Sancho-Cantus, David Martínez-Rubio, Jesús Privado, Jorge Alarcón-Jiménez, Carlos Villarón-Casales, Nieves de Bernardo, Esther Navarro Illana, and José Enrique de la Rubia Ortí
Associations between Mediterranean Diet adherence, quality of life, and mental health in patients with multiple sclerosis: a cross-sectional study
Antonios Dakanalis, Christina Tryfonos, Eleni Pavlidou, Konstantinos Vadikolias, Sousana K. Papadopoulou, Olga Alexatou, Theofanis Vorvolakos, Maria Chrysafi, Dimitrios Fotiou, Maria Mentzelou, Aspasia Serdari, Maria Chatzidimitriou, Sophia Dimoliani, Gerasimos Tsourouflis and Constantinos Giaginis
Positive and Negative Syndrome Scale (PANSS)
Amisulpride augmentation therapy improves cognitive performance and psychopathology in clozapine-resistant treatment-refractory schizophrenia: a 12-week randomized, double-blind, placebo-controlled trial
Ming-Huan Zhu, Zhen-Jing Liu, Qiong-Yue Hu, Jia-Yu Yang, Ying Jin, Na Zhu, Ying Huang, Dian-Hong Shi, Min-Jia Liu, Hong-Yang Tan, Lei Zhao, Qin-Yu Lv, Zheng-Hui Yi, Feng-Chun Wu & Ze-Zhi Li
Differences in inflammatory marker profiles and cognitive functioning between deficit and nondeficit schizophrenia
Dandan Wang, Yewei Wang, Yan Chen, Lingfang Yu, Zenan Wu, Ruimei Liu, Juanjuan Ren, Xinyu Fang and Chen Zhang
Factor analysis of the relationship between PANSS score and family burden of patients with schizophrenia
Jiang Huang, Wei-Xiang Wei, Pan-Pan Zheng, Tao Tang, Pei-Hao Zhang, Mao-Yuan Long, Mei-Ling Li, Xiao-Yu Ning, Ying-Yun Tian, Yu Cheng, Jun Wu
Multimodal brain deficits shared in early-onset and adult-onset schizophrenia predict positive symptoms regardless of illness stage
Aichen Feng, Na Luo, Wentao Zhao, Vince D. Calhoun, Rongtao Jiang, Dongmei Zhi, Weiyang Shi, Tianzi Jiang, Shan Yu, Yong Xu, Sha Liu, Jing Sui
Pentoxifylline as an adjunctive in treatment of negative symptoms in chronic schizophrenia: A double-blind, randomized, placebo-controlled trial
Mahmoud S. Abdallah, Esraa M. Mosalam, Ahmed Hassan, Ahmed N. Ramadan, Hend Omara-Reda, Abdel-Aziz A. Zidan, Waad A. Samman, Eman I. El-berri
Relationship between clinical outcomes measures and personal and social performance functioning in a prospective, interventional study in schizophrenia
Roland Vauth, Bernardo Carpiniello, Jacek Turczyński, Mikhail Ivanov, Pierre Cherubin, Marjolein Lahaye, Andreas Schreiner
Repeatable Battery for the Assessment of Neuropsychological Status® (RBANS®)
Aberrant static and dynamic functional patterns of frontoparietal control network in antipsychotic-naïve first-episode psychosis subjects
Frederic Briend, William P. Armstrong, Nina V. Kraguljac, Shella D. Keilhloz, Adrienne C. Lahti
Altered Intrinsic Brain Activity in Patients With Late-Life Depression: A Resting-State Functional MRI Study
Chaomeng Liu, Weigang Pan, Dandi Zhu, Peixian Mao, Yanping Ren, and Xin Ma
Amisulpride augmentation therapy improves cognitive performance and psychopathology in clozapine-resistant treatment-refractory schizophrenia: a 12-week randomized, double-blind, placebo-controlled trial
Ming-Huan Zhu, Zhen-Jing Liu, Qiong-Yue Hu, Jia-Yu Yang, Ying Jin, Na Zhu, Ying Huang, Dian-Hong Shi, Min-Jia Liu, Hong-Yang Tan, Lei Zhao, Qin-Yu Lv, Zheng-Hui Yi, Feng-Chun Wu & Ze-Zhi Li
Differences in inflammatory marker profiles and cognitive functioning between deficit and nondeficit schizophrenia
Dandan Wang, Yewei Wang, Yan Chen, Lingfang Yu, Zenan Wu, Ruimei Liu, Juanjuan Ren, Xinyu Fang and Chen Zhang
Electroconvulsive therapy treatment responsive multimodal brain networks
Shile Qi, Christopher C. Abbott, Katherine L. Narr, Rongtao Jiang, Joel Upston, Shawn M. McClintock, Randall Espinoza, Tom Jones, Dongmei Zhi, Hailun Sun, Xiao Yang, Jing Sui, Vince D. Calhoun
Wechsler Abbreviated Scale of Intelligence (WASI)
Alterations in Human Hippocampus Subregions across the Lifespan: Reflections on White Matter Structure and Functional Connectivity
Jianling Tan, Zhongyan Wang, Yi Tang, and Yin Tian
Wechsler Adult Intelligence Scale® (WAIS®)
Cognitive correlates of dual tasking costs on the timed up and go test in Parkinson disease
Ashley Harrie, Benjamin M. Hampstead, Cate Lewis, Emily Herreshoff, Vikas Kotagal
Cognitive profiles in bipolar I disorder and associated risk factors: Using Wechsler adult intelligence scale—IV
Hayoung Ko, DongYeon Park, Jaehyun Shin, Rina Yu, Vin Ryu and Wonhye Lee
Financial Incapacity of Patients with Mild Alzheimer’s Disease: What Neurologists Need to Know about Where the Impairment Lies
Vaitsa Giannouli and Magda Tsolaki
Neuropsychological performance in patients with focal drug-resistant epilepsy and different factors that affect their performance
Nirmeen A. Kishk, Marwa Farghaly, Amani Nawito, Reham Mohamed Shamloul & Mona K. Moawad
Processing speed and working memory are predicted by components of successful aging: a HUNT study
Ingunn Bosnes, Ole Bosnes, Eystein Stordal, Hans M. Nordahl, Tor Å. Myklebust & Ove Almkvist
Criterion-Related Validation of a Music-Based Attention Assessment for Individuals with Traumatic Brain Injury
Eunju Jeong and Susan J. Ireland
Wechsler Intelligence Scale for Children® (WISC®)
Callous–Unemotional Traits and Intelligence in Children with Externalizing Behavioral Problems
Pamela Fantozzi, Pietro Muratori, Valentina Levantini, Irene Mammarella, Gabriele Masi, Annarita Milone, Alessia Petrucci, Federica Ricci, Annalisa Tacchi, Chiara Cristofani and Elena Valente
Network Analysis of ADHD Symptoms and Cognitive Profiles in Children
Zhou Q, Ye X, Wei C, Wu Y, Ren P, Lin X, Li L, Xiang W , Xiao L
The Efficacy and Cognitive Impact of Perampanel Monotherapy in Patients with Self-Limited Epilepsy with Centrotemporal Spikes: A Retrospective Analysis
Xuan Yue, Xiao-Ming Liu, Jiao Chen, Hai-Yun Chen, Qian-Qian Tan, Yong Zhou
Efficacy and safety of transcranial direct current stimulation over the left dorsolateral prefrontal cortex in children and adolescents with attention-deficit/hyperactivity disorder: a randomized, triple-blinded, sham-controlled, crossover trial
Rachel Silvany Quadros Guimarães, Igor D. Bandeira, Bianca Lima Barretto, Thamires Wanke, Clara Oliveira Carvalho Alves, Thiago Lima Barretto, Chrissie Ferreira de Carvalho, Ingrid Dorea-Bandeira, Arthur Tolentino, Daniel H. Lins-Silva, Pedro H. Lucena, Rita Lucena
Genetic predictors of neurocognitive outcomes in survivors of pediatric brain tumors
Sydney T. Grob, Kristen R. Miller, Bridget Sanford, Andrew M. Donson, Kenneth Jones, Andrea M. Griesinger, Vladimir Amani, Nicholas K. Foreman, Arthur Liu, Michael Handler, Todd C. Hankinson, Sarah Milgrom & Jean M. Mulcahy Levy
Wechsler Memory Scale-Fourth Edition (WMS)
Practice effect and test–retest reliability of the Wechsler Memory Scale-Fourth Edition in people with dementia
Shu-Chun Lee, Tzu-Hua Chien, Chih-Pang Chu, Yen Lee and En-Chi Chiu
Wechsler Preschool and Primary Scale of Intelligence® (WPPSI®)
Association between head circumference at two years and second and fifth year cognition
Beena Koshy, Manikandan Srinivasan, Timiri Palani Murugan, Anuradha Bose, Pamela Christudoss, Venkata Raghava Mohan, Sushil John, Reeba Roshan & Gagandeep Kang
Ketogenic diet for epilepsy control and enhancement in adaptive behavior
Omnia Fathy El-Rashidy, May Fouad Nassar, Wafaa Abdelwahab Shokair & Yasmin Gamal Abdou El Gendy
Adaptive behavior assessed by Vineland-3 as comprehensive outcome measure in vanishing white matter
Daphne H. Schoenmakers, Irene van Beelen, Marije M.C. Voermans, Denise Perik, Menno D. Stellingwerff, Nicole I. Wolf, Johannes Berkhof, Marjo S. van der Knaap
Efficacy and safety of transcranial direct current stimulation over the left dorsolateral prefrontal cortex in children and adolescents with attention-deficit/hyperactivity disorder: a randomized, triple-blinded, sham-controlled, crossover trial
Rachel Silvany Quadros Guimarães, Igor D. Bandeira, Bianca Lima Barretto, Thamires Wanke, Clara Oliveira Carvalho Alves, Thiago Lima Barretto, Chrissie Ferreira de Carvalho, Ingrid Dorea-Bandeira, Arthur Tolentino, Daniel H. Lins-Silva, Pedro H. Lucena, Rita Lucena